Publications

CANCER, Optical Detection

Yasaman Ardeshirpour, Rafal Zielinski, Victor Chernomordik, Jacek
Capala, Gary Griffiths, Olga Vasalatiy, Aleksandr V. Smirnov, Jay R.
Knutson, Ilya Lyakhov, Samuel Achilefu, Amir Gandjbakhche, Moinuddin
Hassan: In vivo Fluorescence Lifetime Imaging Monitors Binding of
Specific Probes to Cancer Biomarkers. PLoS ONE, 2012 in press.

Lyakhov I, Zielinski R, Kuban M, Kramer-Marek G, Fisher R, Chertov O, Bindu L, Capala J: HER2- and EGFR-Specific Affiprobes: Novel Recombinant Optical Probes for Cell Imaging, Chembiochem. 2010 Feb 15;11(3):345-50.

CANCER, Personalized Medicine

Zielinski R, Lyakhov I, Jacobs A, Chertov O, Kramer-Marek G, Francella N, Stephen A, Fisher R, Blumenthal R, Capala J.: Affitoxin--a novel recombinant, HER2-specific, anticancer agent for targeted therapy of HER2-positive tumors, J Immunother. 2009Oct;32(8):817-25.

CANCER, Inflammation

Shakhov A.N., Rubtsov A.V., Lyakhov I.G., Tumanov A.V., and Nedospasov S.A.: SPLASH (PLA2IID), a Novel Member of Phospholipase A2 Family, is Associated with Lymphotoxin Deficiency, Genes Immun. 2000 Feb;1(3):191-9. [PDF]

CANCER

I. Lyakhov, A. Krishnamachari, T. Schneider: Discovery of novel tumor suppressor p53 response elements using information theory. Nucleic Acids Res. 2008; 36(11):3828-33 [PDF]

Shakhov AN, Lyakhov I.G., Tumanov AV, Rubtsov AV, Drutskaya LN, Marino MW, Nedospasov SA.: Gene Profiling Approach in the Analysis of Lymphotoxin and TNF Deficiencies. J Leukoc Biol. 2000 Jul;68(1):151-7. [PDF]

Chichkova NV, Evstafieva AG, Lyakhov I. G., Tsvetkov AS, Smirnova TA, Karapetian RN, Karger EM, Vartapetian AB: Divalent Metal Cation Binding Properties of Human Prothymosin Alpha, Eur J Biochem. 2000 Aug;267(15):4745-52. [PDF]

Vartapetian A., Lukashev D., Lyakhov I. G., Belyaeva A., Chichkova N., and Bogdanov A.: Mammalian Prothymosin a Links to tRNA in Escherichia Coli Cells.RNA. 1997 October; 3(10): 1173–1181. [PDF]

Bogdanov A.A., Vartapetian A.B., Lukashev D.E., Lyakhov I. G., Makarova T.N., Chichkova N.V.: Cloning and Expression of Bacterial Gene of Prothymosin Alpha and Search for Functions of Prothymosin Alpha. Mol. Genet. Microbiol. Vir. (Russia), 4: 31, 1994.

BIOINFORMATICS

Z. Chen, K. Lewis, R. Shultzaberger, I. Lyakhov, M. Zheng, B. Doan, G. Storz, T. Schneider: Discovery of Fur binding site clusters in Escherichia coli by information theory models. Nucleic Acids Res. 2007;35(20):6762-77. Epub 2007 Oct 5.

R. Shultzaberger, L. Roberts, I. Lyakhov, R. Fisher, T. Schneider: Correlation between the Binding Rate Constants and the Individual Information of E. coli Fis Binding Sites. Nucleic Acids Res. 2007;35(16):5275-83. Epub 2007 Jul 7.

P.N. Hengen, I.G. Lyakhov, L.E. Stewart and T.D. Schneider: Molecular Flip-Flops Formed by Overlapping Fis Sites, Nucleic Acids Research, 31:6663-6673, 2003. 31 (22): 6663-6673. [PDF]

I.G. Lyakhov, P.N. Hengen, D. Rubens and T.D. Schneider: The P1 Phage Replication Protein RepA Contacts an Otherwise Inaccessible Thymine N3 Proton by DNA Distortion or Base Flipping, Nucleic Acids Research, 29:4892-4900, 2001. 29 (23): 4892-4900 [PDF]

PHYSICS

G.A. Lyakhov, N.V. Suyazov, and I.G. Lyakhov: Noise-induced phase transitions in kinetics of biological populations, Physics of Vibrations, 9: 27-42, 2001.

G.A. Lyakhov, I.G. Lyakhov: Stochastic Hydrogen Bond as a Mechanism of Overcooled Water Stratification. Physics of Vibrations, 8:148-52, 2000.

G.A. Lyakhov, I.G. Lyakhov: Noise-induced Phase Transitions in Biochemical and Population Kinetics: Relation to Equations of Liquid State, Physics of Vibrations, 8: 143-7, 2000.

NANOTECHNOLOGY

I.G. Lyakhov, G.A. Lyakhov, and N.V. Suyazov: Orientational Ordering of Protein Particles with Asymmetric Introductions of Ferritin in a Magnetic Field. Physics of Wave Phenomena, 15(2): 95-105, 2007.

I.G. Lyakhov, T.D. Schneider, G.A. Lyakhov, and N.V. Suyazov: Orientation Ordering of Protein Micro- and Nanoparticles in a Nonuniform Magnetic Field, Physics of Wave Phenomena, 13(1), 2005.

MICROBIOLOGY

Vartapetian A., Chichkova N., Lyakhov I, Makarova T., Evstafieva A., and Bogdanov A.: Segments of Escherichia Coli Genome Similar to the Exons of Human Prothymosin a Gene. FEBS Lett. 1992 Nov 23;313(2):95-7. [PDF]